Relifen vet injection(Ketoprofen 100 mg/ml)
Therapeutic Group: Animal Health
Presentation
Relifen vet injection: Each ml contains Ketoprofen BP 100 mg.
Description
Ketoprofen injection is a potent, non-narcotic and non-steroidal anti-inflammatory drug
(NSAID) with analgesic, anti-pyretic and anti-inflammatory properties. Ketoprofen is US FDA approved NSAID, highly effective to alleviate pain, inflammation and fever of dairy animals, potent inhibitor of prostaglandin synthesis; it inhibits the biosynthesis of PGE2-a and PGF2-a without affecting the ratio of PGE2-a/PGF2-a. It is well tolerated up to 5 times than the recommended dose for 2-3 times longer than those used for treatment.
Indications
Ketoprofen injection is indicated in arthritis, omarthritis, coxitis, dermatitis, post-operative wound & swelling, abscess, myositis and lamness, inflammation due to injury, relieving fever and pain due to acute mastitis, ephimeral fever, pain of bone and muscle, supportive therapy with antimicrobials, controlling low to medium convulsive pain.
Dosage & Administration
Cattle, Buffalo, sheep & goat: 1 ml(100 mg)/33 kg body weight intramuscularly or intravenously every 24 hours up to 3 days.
Horse: 1 ml(100 mg)/45 kg of body weight intravenously every 24 hours up to 3 days.
Or as directed by the registered Veterinarian.
Side Effects
Ketoprofen injection is tested and clinically well tolerated. However, GI upset may occur as similar to those of other NSAIDs.
Precautions
Special care should be taken in case of severe dehydration, hypovolaemia and hypotension as there is a risk of renal toxicity. Sufficient drinking water must be supplied at all times during or after treatment.
Use in Pregnancy & Lactation
As the effects of Ketoprofen on fertility, pregnancy or foetal health of horses have not been determined, Ketoprofen injection should not be administered to pregnant mares. It may be given to pregnant and lactating cattle with prior caution.
Drug Interaction
Concurrent use of corticosteroids and other NSAIDs may greatly increase the risk of gastrointestinal ulceration and renal papillary necrosis.
Over Dose
Overdoses of Ketoprofen injection can cause GI ulcers, protein loss, kidney and liver damage. Early signs of toxicity include loss of appetite and depression.
Withdrawal Period
Storage
Keep in a cool and dry place, away from light. Keep out of the reach of children.
Commercial Pack
Relifen vet injection 10 ml: Each commercial box contains 1 amber vial of 10ml.