Zervin(Cetirizine 0.24%)

Therapeutic Group: Ophthalmic


Zervinâ„¢Sterile Eye Drops: Each ml contains Cetirizine Dihydrochloride BP equivalent to Cetirizine 2.4 mg.


Zervinis a sterile ophthalmic solution containing Cetirizine, which is a histamine-1 (H1) receptor antagonist, for topical administration to the eyes. Its effects are mediated via selective inhibition of H1 histamine receptors.


Cetirizine 0.24% ophthalmic solution is indicated for the treatment of ocular itching associated with allergic conjunctivitis.

Dosage & Administration

Adults and children (age 2 years and above)
The recommended dosage is to instill one drop in the affected eye(s) twice daily (approximately 8 hours apart).

Side Effects

The most common adverse reactions are ocular hyperemia, instillation site pain and visual acuity reduction.


Care should be taken not to touch the eyelids or surrounding areas with the dropper tip of the bottle to prevent contaminating the tip and solution. Keep the bottle closed when not in use. Patients should be advised not to wear a contact lens if their eye is red. Remove contact lenses prior to instillation of the drug. Lenses may be reinserted after 10 minutes following the drug administration

Use in Pregnancy & Lactation

Pregnancy: There is no adequate or well-controlled study with Cetirizine 0.24% ophthalmic solution in pregnant women. It should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation: It is not known whether the systemic absorption resulting from topical ocular administration of Cetirizine could produce detectable quantities in human breast milk.There is no adequate information regarding the effects of Cetirizine on breastfed infants, or the effects on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for this drug and any potential adverse effects on the breastfed child from Cetirizine.

Pediatric use
The safety and effectiveness have been established in pediatric patients two years of age and older.

Geriatric use
No overall differences in safety or effectiveness have been observed between elderly and younger patients.


• Do not store above 30 ⁰C.
• Do not freeze.
• Protect from light.
• Do not use more than 4 weeks after opening.
• Keep out of the reach of children.

Commercial Pack

Zervinâ„¢ Sterile Eye Drops: Each plastic dropper bottle contains 5 ml sterile eye drops.