Visi Blue(Trypan Blue 0.06%)

Therapeutic Group: Ophthalmic


Visi Blue Sterile Ophthalmic Solution: Each vial contains 1 ml sterile solution of

Trypan Blue 0.6 mg


Visi Blue 0.06% is a sterile solution of Trypan Blue. It is a selective tissue staining

agent (dye) which stains anterior lens capsule of the human crystalline lens. The dye

does not penetrate the capsule, permitting visualization of the anterior capsule in

contrast to the non-stained lens cortex and inner lens material


Trypan Blue is indicated for use as an aid in ophthalmic surgery by staining the

anterior capsule of the lens.

Dosage & Administration

The first step to administer Trypan Blue is to inject an air bubble into the anterior
chamber using a 26 gauge needle. It prevents dilution of dye by the aqueous humor.
Then Trypan Blue is injected into the anterior lens capsule using a tuberculin syringe.
Sufficient staining is achieved as soon as the dye has contracted the capsule. If some
area is left unstained, inject one more drop till it gets stained.

Side Effects

Discoloration of high water content hydrogen intraocular lenses
Inadvertent staining of the posterior lens capsule and vitreous face. It is generally
self limited, lasting up to one week


It is recommended that after injection all excess Trypan Blue should be immediately
removed from the eye by thorough irrigation of the anterior chamber

Use in Pregnancy & Lactation

Pregnancy Category C. There are no adequate and well-controlled studies in
pregnant women. Trypan Blue should be given to a pregnant woman only if the
potential benefit justifies the potential risk to the fetus.
It is not known whether this drug is excreted in human milk. Because many drugs are
excreted in human milk, caution should be exercised when Trypan Blue is
administered to a nursing woman.
Pediatric use
The safety and effectiveness of Trypan Blue have been established in pediatric
patients. Use of Trypan Blue is supported by evidence from an adequate and well
controlled study in pediatric patients.
Geriatric use
No overall differences in safety and effectiveness have been observed between
elderly and younger patients.


Store below 30 0C and keep away from light.

Commercial Pack

Visi Blue Sterile Ophthalmic Solution: Each vial contains 1 ml sterile solution of
Trypan Blue.