Therapeutic Group: Anti Histamine


Neocilor tablet: Each film-coated tablet contains Desloratadine INN 5 mg.

Neocilor syrup: Each 5 ml syrup contains Desloratadine INN 2.5 mg.


Neocilor is a preparation of Desloratadine. Desloratadine is a long-acting tricyclic histamine antagonist with selective H1-receptor antagonist activity. It is a non-sedating antihistamine. Desloratadine has effects on the chronic inflammatory response to allergens and lacks effects on the QT interval of ECG, unlike some other non-sedating antihistamines.


Allergic rhinitis: Neocilor is indicated for the relief of nasal and non-nasal symptoms of allergic rhinitis (seasonal and perennial).

Chronic idiopathic urticaria: Neocilor is indicated for the symptomatic relief of pruritus, reduction in the number of hives and size of hives, in patients with chronic idiopathic urticaria.

Dosage & Administration

As there are no food effects on the bioavailability, Neocilor may be taken without regard to meal.
Adults and adolescent of 12 years or over : 5 mg once daily.
Child 6-11 years : 2.5 mg once daily.
Child 12 months-5 years : 1.25 mg (2.5 ml Neocilor syrup) once daily.
Child 6 months-11 months : 1 mg (2 ml Neocilor syrup) once daily.
Patients with liver or renal impairment: A starting dose of one Neocilor tablet (Desloratadine 5 mg) every other day is recommended.
Pediatric use: The safety and effectiveness of Desloratadine in pediatric patients under 6 months of age has not been established.

Side Effects

Desloratadine is generally well tolerated. However, dry mouth, fatigue, somnolence and myalgia are commonly reported side-effects. Less common side-effects may include dizziness, headache and nausea. Rarely rash, pruritus and urticaria may occur.

Use in Pregnancy & Lactation

Pregnancy: There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, Desloratadine should be used in pregnancy only if clearly needed.
Lactation: Desloratadine passes into breast milk. Therefore, a decision should be made whether to discontinue nursing or to discontinue Desloratadine, taking into account the importance of the drug to the mother.