Toltacox(Toltrazuril)
Therapeutic Group: Anti Protozoal
Presentation
Toltacox: Each ml solution contains Toltrazuril 25 mg.
Description
Toltrazuril is a triazinetrione derivative which is used for the prevention and treatment of Coccidiosis in poultry and turkeys. Light and electron microscope studies show that Toltrazuril is active against all intracellular stages of coccidia, including schizonts, micro and macrogamonts. It interferes with the division of the protozoal nucleus, the activity of the mitochondria and damages the wall forming bodies in the microgametes. That’s why Toltrazuril shows coccidicidal rather than coccidiostatic action. Tottrazuril acts on all intracellular development stages, does not inhibit immunity development, no need follow up treatment, Toltrazuril activity depends on severity of infection, compatible with feed additives and feed medication and has no adverse effects on feed and water intake, weight gain and F.C.R.
Indications
Tottrazuril is indicated for the treatment and prevention of coccidiosis in poultry ( eg. E. tenella, E. necatrix, E. acervulina, E. maxima, E. brunette & E. mitis) and turkeys (eg. E. adenoides, E. meleagrimitis, E. maleagridis & E. gallopavonis).
Dosage & Administration
Treatment: 7 mg/kg body weight or 1ml/liter of drinking water or 28 ml/100 kg flocks for 2 consecutive days; 24 hours continuously or 8 hours each day in drinking water. In severe infections, the treatment may be repeated 5 days later.
Prevention: 7 mg/kg body weight for 2 consecutive days within 10-18 days per month up to 4 months of age as a strategic administration program.
Or as Directed by the registered Veterinarian.
Side Effects
Toltrazuril is well tolerated at recommended dose. However, at high dosages, egg-drop in laying-hens, growth inhibition in broilers and polyneuritis may be reported.
Precautions
Should supply the medicated drinking water as the only source of drinking water.
Drug Interaction
Toltrazuril is compatible with other poultry feed additives & no hazardous reactions were reported.
Over Dose
Sufficient data is not available.
Withdrawal Period
Meat
Chickens: 8 days.
Turkeys: 21 days.
Egg: Not required.
Storage
Protect from light & keep in a cool and dry place. Keep out from reach of children.
Commercial Pack
Toltacoxl: Each bottle contains 100 ml of solution.