Synogen(Undenatured type II Collagen)

Therapeutic Group: Bone and Joint Disorder


Synogen Capsule: Each delayed release capsule contains Undenatured type II Collagen 40 mg.


Synogen contains Undenatured type II Collagen also known as Chicken Collagen type II that works by oral tolerization. This Undenatured type II Collagen contains epitopes that interacts with the peyer’s patch in the intestine. It prevents the immune system from releasing destructive collagen specific T-cell. This T-cell is responsible for degradation of collagen in the joints. This causes halting the erosion of joint cartilage. As inflammation subsides the disequilibrium of cartilage turnover shifts in favor of rebuilding. It appears that once the destructive cycle is broken, the joint cartilage begins to repair itself through collagen building activities that are part of normal cartilage remodelling process.


The drug is indicated to treat osteoarthritis, rheumatoid arthritis, other joint pain & inflammation associated with injury and impaired joint function.

Dosage & Administration

1 capsule daily with meal or as directed by the physician.

Side Effects

Generally safe for most of the people but some may feel stomach problems.


Caution should be taken if patient is allergic to chicken. The drug is not indicated to use in children and patient under 18 years of age

Use in Pregnancy & Lactation

There is not enough reliable information about the safety of taking Undenatured type II Collagen if you are pregnant or breast-feeding. So it is better to avoid the drug during pregnancy and lactation.

Drug Interaction

There is no known drug interaction.

Over Dose

Abdominal discomfort may happen in case of overdose of drug.

Commercial Pack

Synogen Capsule: Each box contains 5 Alu-Alu blister strips of 4 capsules.