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Lamivir (Lamivudine)
Therapeutic Group: Anti Viral » Hepatitis B Medication
Presentation
Lamivir

Lamivir: Each film coated tablet contains Lamivudine INN 100 mg.

Descriptions
Lamivudine is a synthetic nucleoside analogue with activity against Hepatitis B Virus (HBV) and Human Immunodeficiency Virus (HIV).
Indications
Lamivir is indicated for the treatment of chronic hepatitis B associated with evidence of hepatitis B viral replication and active liver inflammation.
Dosage & Administration
The recommended dose of Lamivudine for the treatment of chronic hepatitis B in adults is 100 mg once daily. The recommended dose for pediatric patients of 2 to 17 years of age is 3 mg/kg once daily up to a maximum daily dose of 100 mg. Treatment should be continued if there is no loss of efficacy and until adequate seroconversion is achieved.
Side Effects
Nausea, vomiting, diarrhoea, abdominal pain, cough, headache, insomnia, malaise, fever, rash, alopecia, muscle disorders, nasal symptoms, peripheral neuropathy may occur. Sometimes neutropenia and anemia; thrombocytopenia; lactic acidosis, raised liver enzymes and serum amylase have been reported.
Precautions
Patients should be assessed before giving treatment with Lamivudine. Safety and efficacy of Lamivudine have not been established in patients with decompensated liver disease, pediatric patients, patients dually infected with Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV), Hepatitis Delta. Reduction in dosage is recommended for patients with impaired renal function.
Contraindications
Lamivudine is contraindicated in patients with hypersensitivity to any of the components of the product.
Use in Pregnancy & Lactation
There are no adequate and well controlled studies in pregnant woman. Lamivudine should be used in pregnancy if the potential benefits outweigh the risks. Mother should be instructed not to breastfeed if they are receiving Lamivudine.
Commercial Packaging
Lamivir : Each box contains 2 blister strips of 10 tablets.
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