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Iriban (Mebeverine)
Therapeutic Group: Gastro Intestinal Disorders » Irritable Bowel Syndrome
Presentation

Iriban 135 tablet: Each tablet contains Mebeverine Hydrochloride BP 135 mg.

Iriban SR 200 capsule: Each SR capsule contains Mebeverine Hydrochloride BP 200 mg.

Descriptions
Iriban is a musculotropic antispasmodic agent used to relieve cramps or spasms of the stomach and intestine (gut). It is particularly useful in treating irritable bowel syndrome (IBS) and similar conditions. It works by relaxing the muscles and helping restore the normal movement of the gut.
Indications
Iriban is indicated:

For the symptomatic treatment of irritable bowel syndrome (IBS)

Other conditions include:

Chronic irritable colon

Spastic constipation

Mucous colitis

Colicky abdominal pain

Persistent non-specific diarrhoea

Dosage & Administration
Adults, elderly and children over 10 years: 1 tablet three times, or 1 capsule twice daily

Iriban is most effective when taken 20 minutes before meals. After several weeks when the desired effect has been obtained, the dosage may be gradually reduced.

*Missed dose: If a dose of this medicine is missed, that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.
Side Effects
Generally Mebeverine is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.
Precautions
Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.
Contraindications
Not known
Use in Pregnancy & Lactation
No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised.

Mebeverine does not excrete in the breast milk after administering the therapeutic dose.

Use in children
Mebeverine is not recommended in children under 10 years.
Drug Interaction
Not known
Overdose
On theoretical grounds it may be predicted that CNS excitability will occur in case of overdosage. No specific antidote is known: gastric lavage and symptomatic treatment is recommended.
Commercial Packaging
Iriban 135 tablet: Each box contains 5 blister strips of 10 tablets.
Iriban SR 200 capsule: Each box contains 3 blister strips of 10 capsules.
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