Home > Products > Remtin
Share Print This Page

Remtin (Memantine Hydrochloride)
Therapeutic Group: Drugs of Nervous System » Anti Alzheimers
Presentation
Remtin

Remtin: Each film coated tablet contains Memantine Hydrochloride 5 mg.

Descriptions
Memantine Hydrochloride is a low affinity, voltage dependent, uncompetitive NMDA (N-methyl-D-aspartate) receptor antagonist. Persistant activation of NMDA receptors in central nervous system by the excitatory amino acid glutamate contributes to the symptomatology of Alzheimar’s disease. Memantine exert its therapeutic effect through its action as a low to moderate affinity uncompetitive NMDA receptor antagonist and binds preferentially to the NMDA receptor-operated cation channels.
Indications
Remtin (Memantine Hydrochloride) is indicated for the treatment of moderate to severe dementia of the Alzheimar’s type.
Dosage & Administration
The recommended starting dose of Remtin is 5 mg once daily and the maintanence dose is 20 mg/day. In order to reduce the risk of side effects this dose is achieved gradually by the following treatment scheme:
a) 1st week:
- Morning dose:1 tablet ; Night dose: None
b) 2nd week:
- Morning dose:1 tablet ; Night dose: 1 tablet
c)3rd week:
- Morning dose:2 tablets ; Night dose: 1 tablet
d) 4th week and beyond:
- Morning dose:2 tablets ; Night dose: 2 tablets
Remtin can be taken with or without food.
In case of renal impairment: A target dose of 5 mg BID is recommended in patients with severe renal impairment (creatinine clearance: 5-29 ml/min).
In case of hepatic impairment: No dosage adjustment is needed in patients with mild or moderate hepatic impairment. Remtin should be administered with caution to patients with severe hepatic impairment.
Side Effects
The most common side effects (frequency 2% and less) are hallucinations, confusion, dizziness, headache and tiredness. Uncommon side effects are anxiety, hypertonia (increased muscle tone), vomiting, bladder infections and increased sexual drive.In case of epileptic seizure patients, Remtin may increase the chances of at least one occurring.
Precautions
Remtin has not been systematically evaluated in patients with seizure disorder. Conditions that raise urine pH may decrese the urinary elimination of Memantine resulting in increased plasma levels of Memantine. There is no evidence of carcinogenesis, mutagenesis and impairment of fertility.
Contraindications
Remtin (Memantine Hydrochloride) is contraindicated in patients with known hypersensitivity to Memantine Hydrochloride or to any excipients used in the formulation.
Use in Pregnancy & Lactation
Pregnancy: Pregnancy Category B.
Nursing mothers:It is not known whether Memantine is excreted in human milk and therefore caution should be exercised when Memantine is administered to a nursing mother.
Drug Interaction
Use with other NMDA antagonists e.g. amantadine, ketamine & dextromethorphan has not been systematically evaluated. Drugs that are eliminated via renal mechanisms e.g. hydrochlorothiazide, triametrene, metformin, cimetidine, ranitidine, quinidine & nicotine are contraindicated. Drugs that make urine alkaline e.g. carbonic anhydrase inhibitors, sodium bicarbonate etc. are also contraindicated when given with memantine.
Overdose
Signs and symptoms associated with memantine overdosage in clinical trials include agitation, confusion, ECG changes, loss of consciousness, psychosis, restlessness, slowed movement, somnolence, stupor, unsteady gait, visual hallucinations, vertigo, vomiting and weakness.
Commercial Packaging
Remtin®: Each box contains 3 blister strips of 10 tablets.
Products from the same therapeutic group
Drugs of Nervous System
Anti Alzheimers
Ameloss
Donepezil Hydrochloride tablet
Remtin
Memantine Hydrochloride INN tablet
Anti Depressant
Arpolax
Citalopram tablet
Duloxen
Duloxetine Hydrochloride tablet
Esipram
Escitalopram INN 5 & 10 mg tablet
Mitaprex
Mirtazapine 15 and 30 mg Tablet
Nortilin
Nortriptyline HCl BP 10 mg and 25 mg Tablet.
Pramin
Imipramine HCl BP 25 mg tablet
Repose
Sertraline
Tenaxit
Flupentixol-Melitracen tablet
Anti Epileptic
Barbit
Phenobarbital BP
Oxazep
Oxcarbazepine INN
Valex
Sodium Valproate tablet and syrup
Valex CR
Sodium Valproate tablet/syrup
Anti Migraine
Migrex
Tolfenamic acid BP 200 mg
Topirva
Topiramate tablets
Zomitan
Zolmitriptan tablet
Anti Parkinsons
Cyclid
Procyclidine Hydrochloride
Trihexy
Trihexyphenidyl Hydrochloride USP
Anti Psychotic
Aripra
Aripiprazole tablet
Fenazine
Fluphenazine Decanoate BP
Flurazine
Trifluoperazine Hydrochloride BP
Frenia
Risperidone tablet
Halopid
Haloperidol BP
Lithin SR
Lithium Carbonate BP 400 mg
Olanap
Olanzapine
Quiet
Quetiapine Fumarate INN
Zapenia
Clozapine BP Tablet
Anti Vertigo
Menaril
Betahistine Dihydrochloride Tablet
Revert
Cinnarizine-Dimenhydrinate tablet
Anxiolytic and Tranquilizer
Disopan
Clonazepam tablet & Drops
Lozicum
Lorazepam 1 mg tablet
Siesta
Bromazepam USP 3 mg
Zolium
Alprazolam tablet
Zopilone
Eszopiclone tablet
Hypnitic
Somarant
Suvorexant 10 mg Tablet
Memory Enhancer
Vinsetine
Vinpocetine 5mg Tablet
Neuropathy Neuralgia
Gabapen
Gabapentin tablet
Mecolagin
Mecobalamin
Pregaben
Pregabalin Capsule
 
 

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin schoenen shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest replica handbags model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first replica designer handbags. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like replica handbags uk. Sometimes, you will find cheap replica handbags online. But they are high quality replica handbags. Best replica handbags outlet for girls. The 1:1 replica bags are also perfect. Luxury designer replica handbags for sale online.