Home > Products > Moxquin
Share Print This Page

Moxquin (Moxifloxacin Hydrochloride)
Therapeutic Group: Anti Bacterial

Moxquin 400: Each film coated tablet contains Moxifloxacin Hydrochloride USP equivalent to Moxifloxacin 400 mg.

Moxquin 400 mg IV infusion : Each bottle contains 250 ml solution containing Moxifloxacin Hydrochloride BP equivalent to Moxifloxacin 400 mg.

Moxifloxacin is a synthetic broad spectrum, flouroquinolone derivative antibacterial agent. Moxifloxacin has in vitro activity against a wide range of Gram-positive and Gram-negative microorganisms. The bactericidal action of Moxifloxacin results from inhibition of the topoisomerase II (DNA gyrase) and topoisomerase IV required for bacterial DNA replication, transcription, repair and recombination.
Moxifloxacin is indicated for the treatment of adults (>18 years of age) with infections caused by susceptible strains of the designated microorganisms in the conditions listed below-

- Acute Bacterial Sinusitis caused by Streptococcus pneumoniae, Haemophilus influenzae or Moraxella


- Acute Bacterial Exacerbation of Chronic Bronchitis caused by Streptococcus pneumoniae, Haemophilus

influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, methicillin-susceptible Staphylococcus aureus or

Moraxella catarrhalis

- Community Acquired Pneumonia caused by Streptococcus pneumoniae (including multi-drug resistant strains),

Haemophilus influenzae, Moraxella catarrhalis, methicillin-susceptible Staphylococcus aureus, Klebsiella

pneumoniae, Mycoplasma pneumoniae or Chlamydophilia pneumoniae

- Uncomplicated Skin and Skin Structure Infections caused by methicillin-susceptible Staphylococcus aureus or

Streptococcus pyogenes

- Complicated Skin and Skin Structure Infections caused by methicillin-susceptible Staphylococcus aureus,

Escherichia coli, Klebsiella pneumoniae or Enterobacter cloacae

- Complicated Intra-Abdominal Infections including polymicrobial infections such as abscess caused by

Escherichia coli, Bacteroides fragilis, Streptococcus anginosus, Streptococcus constellatus, Enterococcus faecalis,

Proteus mirabilis, Clostridium perfringens, Bacteroides thetaiotaomicron or Peptostreptococcus species.
Dosage & Administration
• The dose of Moxifloxacin is 400 mg once every 24 hours. The duration of therapy depends on the type of infection as described bellow-
• In Acute Bacterial Sinusitis Moxifloxacin 400 mg is given once daily for 10 days.
• In Acute Bacterial Exacerbation of Chronic Bronchitis Moxifloxacin 400 mg is given once daily for 5 days.
• In Community Acquired Pneumonia Moxifloxacin 400 mg is given once daily for 7-14 days.
• In Uncomplicated Skin & Skin Structure infections Moxifloxacin 400 mg is given once daily for 7 days.
• In Complicated Skin & Skin Structure infections Moxifloxacin 400 mg is given once daily for 7-21 days.
• In Complicated Intra-Abdominal infections Moxifloxacin 400 mg is given once daily for 5-14 days.

Moxquin 400 mg IV infusion can be administered intravenously for the entire treatment duration. Alternatively, therapy may be initial intravenous administration, followed by oral administration when clinically indicated. The recommended duration of treatment for the indication being treated should not be exceeded. The solution for infusion should be infused intravenously over 60 minutes.

No adjustment of dosage is required in the elderly.
Efficacy and safety of Moxquin IV infusion in children and adolescent have not been established.
Side Effects
The following one or more side effects may be observed: tendinopathy and tendon rupture, QT prolongation, hypersensitivity reactions, clostridium difficile-associated diarrhea, peripheral neuropathy, photosensitivity, phototoxicity etc.
Moxifloxacin should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity. Moxifloxacin should be discontinued if the patient experiences pain, swelling, inflammation or rupture of a tendon.
Moxifloxacin is contraindicated in persons with a history of hypersensitivity to Moxifloxacin or any member of the quinolone class of antimicrobial agents and any component of this formulation.
Use in Pregnancy & Lactation
Pregnancy Category C. Moxifloxacin is not recommended during pregnancy & lactation.
Drug Interaction
No quinolone should be co-administered with any solution containing multivalent cations (e.g. magnesium) through the same intravenous line. Antacids, iron and adsorbents reduce absorption of Moxifloxacin. NSAID may increase the risk of CNS stimulation. Warfarin may increase the risk of bleeding.
In the events of an acute overdosage, the stomach should be emptied. The patients should be kept under observation and appropriate hydration should be maintained.
Commercial Packaging
Moxquin 400: Each box contains 2 blister strips of 4 tablets.
Moxquin 400 mg IV infusion: Each box contains a bottle of 250 ml solution, a bottle hanger and an infusion set.
Products from the same therapeutic group
Anti Bacterial
Cefadroxil Capsule 500 mg Powder for suspension Powder for paediatric drops
Amikacin injection
Aztreonam 1 gm for Injection (Sterile).
Ciprofloxacin Tablet, Suspensio & IV Infusion
Cefuroxime & Clavulanic Acid Tablet
Ceftibuten 400mg Capsule
Cefotaxime Injection
Imipenem USP 500 mg & Cilastatin USP 500 mg IV Injection
Clindamycin 150 & 300 mg capsule and 300 mg & 600 mg IV/IM Injection
Cefpodoxime+ Clavulanic acid Tablet
Cefixime Trihydrate USP
Erythromycin Tablets/Suspension
Meropenem Injection
Gentamicin Sulfate USP
Clarithromycin 250 and 500 mg Tablet
Levofloxacin 250, 500 & 750 mg tablets, 100 ml oral solution, 100 ml IV infusion.
Linezolid Tablet, Powder for Suspension and IV Infusion
Moxifloxacin Hydrochloride 400 mg Tablet
Neomycin Sulphate BP & Bacitracin Zinc USP
Nitrofurantoin tablet
Orasquin  Tablet
Gemifloxacin film coated tablet
Cefaclor Monohydrate Capsule/Dry suspension/Paediatric drops
Roxithromycin tablet/powder for suspension
Rifaximin 200 and 550 mg Tablet
Ceftazidime IV/IM
Tigecycline 50 mg as lyophilized powder for Infusion.
Spectinomycin IM Injection
Azithromycin Dihydrate USP
Cefpodoxime Proxetil Tablet/Suspension/Paediatric Drops/DS Suspension

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin sneakers shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest christian louboutin model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first louboutin schuhe. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like louboutin. Sometimes, you will find louboutin damen schuhe online. But they are high quality louboutin schuhe deutschland. Best louboutin schuhe outlet for girls. The 1:1 christian louboutin are also perfect. Luxury louboutin schoenen for sale online.