Home > Products > Mitaprex
Share Print This Page

Mitaprex (Mirtazapine)
Therapeutic Group: Drugs of Nervous System » Anti Depressant
Presentation

Mitaprex 7.5 mg: Each tablet contains Mirtazapine USP 7.5 mg

Mitaprex 15 mg: Each tablet contains Mirtazapine USP 15 mg

Mitaprex 30 mg: Each tablet contains Mirtazapine USP 30 mg

Descriptions
Mitprex (Mirtazapine) is a tetracyclic antidepressant belongs to piperazine-azepine group of compounds. The mechanism of action is unknown. Studies suggest that Mirtazapine enhances central noradrenergic and serotonergic activity. Mirtazapine acts as an antagonist at central presynaptic alpha-2 adrenergic inhibitory auto receptors and heteroreceptors that result in an increase central noradrenergic and serotonergic activity. Mirtazapine is a potent antagonist of 5 HT2 and 5HT3 receptors.
Indications
Mitaprex (Mirtazapine) is indicated for the treatment of depression.
Dosage & Administration
Adult: Initially, 15 mg daily; may be increased gradually depending on clinical response. Change dose at intervals of at least 1-2 weeks. Usual effective dose: 15-45 mg daily given as single dose, preferably at bedtime, or in 2 divided doses. It can be taken with or without food.
Children: Safety and efficacy not established.
Geriatric: Use with caution.
Side Effects
The most commonly reported adverse effects with mirtazapine are increase in appetite, weight gain, edema, drowsiness or sedation, dizziness, headache etc.
Precautions
Mirtazapine should be used cautiously in patients with epilepsy or history of seizure, history of mania /hypomania, patients with hepatic or renal impairment; cardiac disorders e.g. conduction disturbances, angina pectoris, recent MI. Hypotension, DM, psychoses, history of bipolar disorder. Stop treatment if jaundice develops. Monitor patient for signs of bone marrow depression. Monitor patient for suicidal tendency. Avoid abrupt withdrawal. May impair ability to drive or operate machinery.
Contraindications
Mirtazapine is contraindicated in patients with hypersensitivity. Do not use with or within 2 weeks of stopping an MAOI; at least 1 week should elapse between discontinuing mirtazapine and initiating any drug which may provoke a serious reaction (e.g. phenelzine)
Use in Pregnancy & Lactation
Mirtazapine Should not be used during pregnancy and lactation.
Drug Interaction
Mirtazapine potentiates sedative effects with alcohol or benzodiazepines, increased plasma levels with potent CYP3A4 inhibitors (e.g. HIV-protease inhibitors, azole antifungals including ketoconazole, erythromycin, nefazodone), reduced plasma levels with carbamazepine and other inducers of CYP3A4 and increased bioavailability with cimetidine.
Storage
Store at 15 °C-30 °C . Protect from light and moisture.
Commercial Packaging
Mitaprex 7.5 mg: Each box contains 3 blister strips of 10 tablets
Mitaprex 15 mg: Each box contains 3 blister strips of 10 tablets
Mitaprex 30 mg: Each box contains 3 blister strips of 10 tablets
Products from the same therapeutic group
Drugs of Nervous System
Anti Alzheimers
Ameloss
Donepezil Hydrochloride tablet
Remtin
Memantine Hydrochloride INN tablet
Anti Depressant
Arpolax
Citalopram tablet
Duloxen
Duloxetine Hydrochloride tablet
Esipram
Escitalopram INN 5 & 10 mg tablet
Mitaprex
Mirtazapine 7.5, 15 and 30 mg Tablet
Mitaprex
Mirtazapine
Pramin
Imipramine HCl BP 25 mg tablet
Repose
Sertraline
Tenaxit
Flupentixol-Melitracen tablet
Anti Epileptic
Barbit
Phenobarbital BP
Lamogin
Lamotrigine BP Tablet
Neurocet
Levetiracetam tablet
Valex
Sodium Valproate tablet and syrup
Valex CR
Sodium Valproate tablet/syrup
Anti Migraine
Florium
Flunarizine Dihydrochloride BP Tablet
Migrex
Tolfenamic acid BP 200 mg
Topirva
Topiramate tablets
Zomitan
Zolmitriptan tablet
Anti Parkinsons
Cyclid
Procyclidine Hydrochloride
Trihexy
Trihexyphenidyl Hydrochloride USP
Anti Psychotic
Aripra
Aripiprazole tablet
Fenazine
Fluphenazine Decanoate BP
Frenia
Risperidone tablet
Halopid
Haloperidol BP
Lithin SR
Lithium Carbonate BP 400 mg
Luradox
Lurasidone hydrochloride 20 & 40 mg Tablet
Olanap
Olanzapine
Panirid
Paroxetine Hydrochloride Hemihydrate BP Tablet
Quiet
Quetiapine Fumarate INN
Zapenia
Clozapine BP Tablet
Anti Vertigo
Menaril
Betahistine Dihydrochloride Tablet
Revert
Cinnarizine-Dimenhydrinate tablet
Anxiolytic and Tranquilizer
Disopan
Clonazepam tablet & Drops
Lozicum
Lorazepam 1 mg tablet
Siesta
Bromazepam USP 3 mg
Zolium
Alprazolam tablet
Hypnitic
Somarant
Suvorexant 10 mg Tablet
Memory Enhancer
Vinsetine
Vinpocetine 5mg Tablet
Neuropathy Neuralgia
Gabapen
Gabapentin tablet
Mecolagin
Mecobalamin
Pregaben
Pregabalin Capsule