Home > Products > Nyclobate NN
Share Print This Page

Nyclobate NN (Clobetasol Propionate, Neomycin Sulphate & Nystatin)
Therapeutic Group: Skin » Steroid Combination
Presentation

Nyclobate NN Cream: Each gram cream contains Clobetasol Propionate BP 0.5 mg (0.05% w/w), Neomycin Sulphate BP 5 mg (0.5% w/w) and Nystatin BP 1,00,000 IU.

Descriptions
Clobetasol Propionate is a highly active corticosteroid with topical anti-inflammatory activity. The major effect of Clobetasol Propionate on skin is a non-specific anti-inflammatory response, partially due to vasoconstriction and decrease in collagen synthesis. Neomycin Sulphate is a broad spectrum antibiotic of the aminoglycoside type and is used to treat infections with bacteria. Nystatin is an antifungal medicine that kills fungi and yeasts by interfering with their cell membranes. The principle action of the preparation is based on the anti-inflammatory activity of the corticosteroid. The broad spectrum antibacterial and anti-candidal activity provided by the combination of Neomycin and Nystatin allow this effect to be utilized in the treatment of conditions which are or are likely to become infected.
Indications
Any inflammatory skin disorders like eczema & psoriasis where secondary bacterial or fungal infection is present, suspected or likely to occur.
Dosage & Administration
Adults and children over 2 years:
• Apply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations therapy should be discontinued when control is achieved.
• In very resistant lesions, especially where there is hyperkeratosis, the anti-inflammatory effect of this preparaton can be enhanced, if necessary, by occluding the treatment area with polythene.
• Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patient's condition being reviewed.
• Repeated short courses of Nyclobate NN may be used to control exacerbations

Elderly: This preparation is suitable for use in the elderly. Caution should be exercised in cases where a decrease in renal function exists and significant systemic absorption of Neomycin Sulphate may occur.

Children: Under 2 years this preparation is not recommended.
Side Effects
Generally this preparation is well tolerated. However, few side effects after prolonged and intensive treatment may cause local atrophic changes in the skin such as thinning, striae, and dilatation of the superficial blood vessels, particularly when occlusive dressings are used, or when skin folds are involved.
Precautions
Long-term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur readily even without occlusion. If used in childhood, or on the face, courses should be limited to 5 days and occlusion should not be used. If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye. If used in psoriasis careful patient supervision is important. Scalp Application: Keep away from eye. Flammable. Do not use or dry the hair near a fire or flame.
Contraindications
It is contraindicated in rosacea, acne vulgaris, perioral dermatitis, primary cutaneous viral infections (eg. herpes simplex, chickenpox), otitis externa with a perforated eardrum, hypersensitivity to the preparations. Scalp application is contraindicated in infection of the scalp.
Use in Pregnancy & Lactation
Pregnancy category C: The safe use of this preparation during pregnancy & lactation has not been established.
Drug Interaction
Neomycin Sulphate can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents following significant systemic absorption. However, if used in accordance with the recommendations systemic exposure to Neomycin Sulphate is expected to be minimal and drug interactions are unlikely to be significant. No hazardous interactions have been reported with use of Clobetasol Propionate or Nystatin.
Overdose
Acute overdosage is very unlikely to occur, however, in the case of chronic overdosage or misuse the features of hypercortisolism may appear and in this situation topical steroids should be discontinued gradually. Also, consideration should be given to significant systemic absorption of Neomycin Sulphate. If this is suspected, use of the product should be stopped and the patient\\\\\\\'s general status, hearing acuity, renal and neuromuscular functions should be monitored. Haemodialysis may reduce the serum level of Neomycin Sulphate.
Commercial Packaging
Nyclobate NN Cream: Each tube contains 10 gm or 20 gm cream.
Products from the same therapeutic group
Skin
Anti Bacterial
Adaben Duo Gel
Adapalene BP 0.1% & Benzoyl peroxide BP 2.5% gel
Clindacin Cream
Clindamycin 2% w/w
Clindacin lotion
Topical Lotion
Clindacin Plus Gel
Clindamycin 1.2% and Tretinoin 0.025% Gel.
Trego
Mupirocin
Anti Fungal
Clarizol
Clotrimazole 1%
Dancel Shampoo
Ketoconazole 2% shampoo
Econate
Econazole Nitrate cream and tablet.
Nispore
Fluconazole 50 mg, 150 mg, 200mg capsule & Powder for Suspension
Oroconazol
Miconazole 2% oral gel
Topicazole
Miconazole Nitrate BP 2% Cream.
Anti Fungal Combination
Econate Plus
Econazole Nitrate and Triamcinolone Acetonide cream
Topicazole Plus
Miconazole Nitrate and Hydrocortisone Acetate
Anti Hyperpigmenting Agent
Colagel
L-Lysine hydrochloride 15% Gel
Solascren
Padimate O 8%, Avobenzone 2%, Oxybenzone 3% &Titanium dioxide 2%
Spotclen
Hydroquinone cream
Spotclen Plus
Hydroquinone 4% cream with sunscreens.
TRIMELA
Fluocinolone acetonide 0.01%, Hydroquinone 4% and Tretinoin 0.05%
Anti Viral
Lafrost
Docosanol cream
Antipruritics
Doxiderm
Doxepin hydrochloride 5%
Emollients
Eudrate
Urea BP 10%
Napguard
Zinc Oxide 40% w/w
Planex
Calcipotriol 0.005% Ointment
Hair Growth Promoter
Xenogrow
Minoxidil topical solution 2%, 5%
Immunomodulator
Aprima
Apremilast 10 mg Tablet
Tacrolim
Tacrolimus 0.03% & 0.1%
Prevention of Keratosis
Kerasol Cream
Salicylic Acid BP
Retinoid
Apalene
Apalene 0.1% Cream
Tazoskin
Tazarotene 0.1% w/w cream.
Scabicide
Elimate Cream
Permethrin
Elimate Plus
Permethrin BP 5% and Crotamiton BP 10%
Steroid Combination
Betaderm N Ointment
Betamethasone 0.1% & Neomycin Sulphate 0.5%
Betamesal Scalp Lotion
Betamethasone 0.05 % & Salicylic Acid 2%
Fortison
Fusidic acid & Hydrocortisone cream
Nyclobate NN
Clobetasol Propionate, Neomycin Sulphate & Nystatin Cream
Steroid Plain
Betaderm Ointment
Betamethasone 0.1%
Lutisone
Fluticasone Propionate Ointment
Momeson Cream
Mometasone Furoate BP 0.1% Cream
Nyclobate
Clobetasol Propionate Cram, Ointment and Scalp Application
Ulticort
Halobetasol Propionate 0.05% Cream
 
 

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin sneakers shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest christian louboutin model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first louboutin schuhe. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like louboutin. Sometimes, you will find louboutin damen schuhe online. But they are high quality louboutin schuhe deutschland. Best louboutin schuhe outlet for girls. The 1:1 christian louboutin are also perfect. Luxury louboutin schoenen for sale online.