Home > Products > Firmac
Share Print This Page

Firmac (Erythromycin)
Therapeutic Group: Anti Bacterial
Presentation

Firmac 250: Each tablet contains Erythromycin Stearate BP equivalent to Erythromycin 250 mg.

Firmac : Each tablet contains Erythromycin Stearate BP equivalent to Erythromycin 500 mg.

Firmac Dry Suspension: After reconstitution, each 5 ml suspension contains Erythromycin Ethylsuccinate BP equivalent to Erythromycin 125 mg.

Descriptions
Erythromycin is highly effective against most strains of the following microorganisms, both in vitro and in clinical infections:

Gram-positive microorganisms: Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Corynebacterium diphtheriae, Corynebacterium minutissimum and Listeria monocytogenes.

Gram-negative microorganisms: Haemophilus influenzae, Bordetella pertusis, Legionella pneumophilia, Campylobacter jejuni and Neisseria gonorrhoeae.

Other microorganisms: Mycoplasma pneumoniae, Chlamydia trachomatis, Entamoeba histolytica, Treponema pallidum and Ureaplasma urealyticum.
Indications
Erythromycin is highly effective in the treatment of great variety of clinical infections caused by Erythromycin sensitive microorganisms.

Upper respiratory tract infections: Tonsillitis, peritonsillar abscess, pharyngitis, laryngitis, sinusitis, secondary infections in cold and influenza.

Lower respiratory tract infections: Tracheitis, acute & chronic bronchitis, pneumonia (lobar pneumonia, bronchopneumonia, primary atypical pneumonia), bronchiectasis, legionnaires' diseases.

Ear infections: Otitis media and Otitis externa, mastoiditis.

Oral infections: Gingivitis, Vincent's angina.

Eye infection: Blepharitis.

Skin & Soft tissue infections: Boils and carbuncles, paronychia, abscesses, pustular acne, impetigo, cellulites, erysipelas.

Gastrointestinal infections: Cholecystitis, staphylococcal enterocolitis.

Prophylaxis: Pre- and Post operative trauma, burns, rheumatic fever.

Other infections: Osteomyelitis, urethritis, gonorrhoea, syphilis, lymphogranuloma venerum, diphtheria, prostitis, scarlet fever.
Dosage & Administration
Adult and Child over 8 years: 250-500 mg every 6 hours or 0.5-1gm every 12 hours. This may be increased up to 4 gm daily according to severity of infections.
Child of 2-8 years: 250 mg every 6 hours, doses doubled for severe infections.
Child up to 2 years: 125 mg every 6 hours.
Neonates: 30 - 45 mg/kg daily in 3 divided doses.
Elderly: Same as for adults.
If administration on a twice daily schedule is desirable, one half of the total daily dose may be given every 12 hours, one hour before meal.
Amoebic dysentery
Adult: 250 - 500 mg four times daily for 10 - 14 days.
Children: 30 - 50 mg/kg/day in divided doses for 10 - 14 days.
Pertussis: 30 - 50 mg/kg/day in divided doses for 5 - 14 days depending upon eradication of a positive culture.
Streptococcal infections: In the treatment of group A beta haemolytic streptococcal infections, therapeutic dosage of Erythromycin should be administered for at least 10 days.
Acne: The usual dosage regimen of erythromycin in the treatment of acne is 500 mg twice daily for 3 months. Then the dose is to be reduced to 250 mg twice daily for another 3 months.
Early Syphilis: 500 mg 4 times daily for 14 days.
Uncomplicated genital Chlamydia nongonococcal Urethritis: 500 mg twice daily for 14 days.
Prophylaxis: In continuous prophylaxis of streptococcal infections in person with a rheumatic heart disease, the dosage is 250 mg twice daily.
When Erythromycin is used prior to surgery to prevent endocarditis caused by alpha haemolytic streptococci, a recommended schedule for children - 20 mg/Kg 1.5 - 2 hours pre-operatively and 10 mg/kg every 6 hours for 8 doses post-operatively. For adults, the dose is 1 g, 1.5 - 2 hours pre-operatively and 500 mg every 6 hours for 8 doses post-operatively.
Side Effects
Generally erythromycin is well tolerated and serious adverse effects are rare. Side-effects are gastrointestinal and are dose-related. They include nausea, vomiting, abdominal pain, diarrhea and anorexia.
Mild allergic reactions, such as urticaria and skin rashes have occurred. Serious allergic reactions, including anaphylaxis may occur.
Precautions
Since Erythromycin is metabolized principally by the liver, caution should be exercised when erythromycin is administered to patients with impaired hepatic function. There have been reports of hepatic dysfunction with or without jaundice occurring in patients taking oral Erythromycin.
Contraindications
Erythomycin is contraindicated in patients with a known hypersensitivity to this drug.
Use in Pregnancy & Lactation
Pregnancy: There are no adequate and well-controlled studies in pregnant women about administration of Erythromycin therefore; this drug should be used during pregnancy only if clearly needed.
Lactation: Erythromycin is excreted in breast milk; therefore, caution should be exercised when Erythromycin is administered to a nursing woman.
Drug Interaction
Theophylline: The use of Erythromycin in patients who are receiving concomitant high doses of theophylline may be associated with an increase in serum theophylline and potential theophylline toxicity. If symptoms of toxicity develop, the dose of theophylline should be reduced.
Digoxin: Concomitant administration of Erythromycin and Digoxin has been reported to result in elevated digoxin serum levels.
Overdose
In case of overdosage, Erythromycin should be discontinued. Overdosage should be handled with the prompt elimination of unabsorbed drug and all other appropriate measures should be instituted.
Erythromycin is not removed by peritoneal dialysis or haemodialysis.
Commercial Packaging
Firmac 250 : Each box contains 5 blister strips of 10 tablets.
Firmac : Each box contains 3 blister strips of 10 tablets.
Firmac Dry Suspension: Bottle containing dry powder for 100 ml suspension.
Others
Direction for reconstitution of suspension
Shake the bottle to loosen powder. Add 60 ml (12 measuring spoonful) of boiled and cooled water to the dry powder of the bottle. For ease of preparation, add water to the bottle in two proportions. Shake well after each addition until all the powder is in suspension.
Note: Shake the suspension well before each use. Keep the bottle tightly closed. The reconstituted suspension should be stored in a cool and dry place, preferably in refrigerator and unused portion should be discarded after 7 days.
Products from the same therapeutic group
Anti Bacterial
Adora
Cefadroxil Capsule 500 mg Powder for suspension Powder for paediatric drops
Amikin
Amikacin injection
Azonam
Aztreonam 1 gm for Injection (Sterile).
Beuflox
Ciprofloxacin Tablet, Suspensio & IV Infusion
Cefaclav
Cefuroxime & Clavulanic Acid Tablet
Cefamax
Ceftibuten 400mg Capsule
Cefotime
Cefotaxime Injection
Cispenam
Imipenem USP 500 mg & Cilastatin USP 500 mg IV Injection
Clindacin
Clindamycin 150 & 300 mg capsule and 300 mg & 600 mg IV/IM Injection
Duo-5
Cefpodoxime+ Clavulanic acid Tablet
Efdinir
Cefdinir Capsule & Dry Suspension
Emixef
Cefixime Trihydrate USP
Exephin
Ceftriaxone
Firmac
Erythromycin Tablets/Suspension
Gatiflox
Gatifloxacin 400 mg Tablet.
I-Penam
Meropenem Injection
Inclox
Flucloxacillin
Intamycin
Gentamicin Sulfate USP
Ipadox
Capsule
Kilbac
Cefuroxime
Klarix
Clarithromycin 250 and 500 mg Tablet
Levoxin
Levofloxacin 250, 500 & 750 mg tablets, 100 ml oral solution, 100 ml IV infusion.
Linzolid
Linezolid Tablet, Powder for Suspension and IV Infusion
Moxquin
Moxifloxacin Hydrochloride 400 mg Tablet
Nebazin
Neomycin Sulphate BP & Bacitracin Zinc USP
Nintoin
Nitrofurantoin tablet
Orasquin  Tablet
Gemifloxacin film coated tablet
Oticlor
Cefaclor Monohydrate Capsule/Dry suspension/Paediatric drops
Pedilid
Roxithromycin tablet/powder for suspension
Procef
Cefradine
Rifamax
Rifaximin 200 and 550 mg Tablet
Sidobac
Ceftazidime IV/IM
Tenafet
Cefetamet Pivoxil Hydrochloride INN
Tigacil
Tigecycline 50 mg as lyophilized powder for Infusion.
Tinobac
Spectinomycin IM Injection
Tridosil
Azithromycin Dihydrate USP
Vanmycin
Vancomycin
Ximeprox
Cefpodoxime Proxetil Tablet/Suspension/Paediatric Drops/DS Suspension
 
 

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin sneakers shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest christian louboutin model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first louboutin schuhe. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like louboutin. Sometimes, you will find louboutin damen schuhe online. But they are high quality louboutin schuhe deutschland. Best louboutin schuhe outlet for girls. The 1:1 christian louboutin are also perfect. Luxury louboutin schoenen for sale online.