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Topicazole Plus (Miconazole Nitrate & Hydrocortisone acetate)
Therapeutic Group: Skin » Anti Fungal Combination
Presentation
Topicazole Plus

Topicazole Plus Cream: Each gram cream contains Miconazole Nitrate BP 20 mg & Hydrocortisone Acetate BP equivalent to Hydrocortisone BP 10 mg.

Descriptions
Miconazole Nitrate is a broad spectrum antifungal agent which is active against

Phycomycetes, Ascomycetes and Adelomycetes (e.g., Saprolegnia, Candida, Cryptococcus, Aspergillus, Dermatophytes, Phialophora, Sporotrichum), and Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum. Trichophyton interdigitale and Microsporum canis. Miconazole nitrate also possesses some anti-bacterial activity against Gram-positive organisms.

Hydrocortisone acetate is a mild topical steroid which reduces inflammation, swelling, redness and itching of the skin.

Indications
It is indicated for the treatment of fungal skin infections such as sweat rash or athlete's foot when additional symptoms of inflammation (such as swelling, redness and itching) is present.
Dosage & Administration
It should be applied topically to the affected area twice daily. Rub it in gently until the cream has disappeared. Do not use the cream for more than 7 days. After using the cream wash hands carefully to avoid spreading the infection to other parts of the body or to other people.
Side Effects
Generally it is well tolerated. An allergic reaction to any of the ingredient of the cream may occur. Rarely, irritation & burning may occur.
Precautions
It should be used with caution when applied to extensive surface areas or under occlusive dressings including baby napkins. Application to the face should be avoided.
Contraindications
The drug is contraindicated in individuals with a history of sensitivity reactions to Miconazole or any of the components of the preparation, viral disease of the skin (herpes, chickenpox), perioral dermatitis, rosaceae, ulcerative conditions, tuberculous or syphilitic processes.
Use in Pregnancy & Lactation
During pregnancy and lactation, this medication should be used only when clearly needed.
Commercial Packaging
Topicazole Plus Cream: Each tube contains 10 gram of Miconazole Nitrate and Hydrocortisone Acetate cream.
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