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Intafenac Eye Drops (Diclofenac 0.1%)
Therapeutic Group: Ophthalmic » NSAID Preparations
Presentation
Intafenac Eye Drops

Intafenac 0.1% eye drops: Each ml contains Diclofenac Sodium BP 1.0 mg.

Descriptions
Diclofenac Sodium works by blocking the action of cyclo-oxygenase. Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause pain, swelling and inflammation.
Indications
- Pre- and post-operative cover (e.g., for cataract surgery)

- Non-infected chronic conjunctivitis, keratoconjunctivitis

- Non-infected post-traumatic conditions of the cornea and conjunctiva

Dosage & Administration
Adults
Pre-operatively: Instill 1 drop in the conjunctival sac up to 5 times over the 3 hours preceding surgery

Post-operatively: Instill 1 drop in the conjunctival sac after 15, 30 & 45 minutes following surgery; then 3-5 times daily for as long as required.

Inflammatory conditions: Instill 1 drop in the conjunctival sac 4-5 times daily depending upon the severity of the diseases.
Side Effects
Mild to moderate burning sensation in 5-15% patients which is transient in nature and almost never necessitated discontinuation of treatment. Other less common side-effects are sensitivity to light, bad taste, feeling of pressure, allergic reactions etc.
Precautions
Intafenac eye drops may mask the signs of infection. So physicians should be alert to the development of infections in patients receiving the drug. During prolonged use, it is recommended that physicians conduct periodic examinations of the eye, including measurement of the intraocular pressure. Contact lenses should not be worn during treatment.
Contraindications
Contraindicated to patients hypersensitive to Diclofenac Sodium or any other of its ingredients. Diclofenac sodium is also contraindicated in patients who may have NSAID induced asthma, urticaria, or acute rhinitis.
Use in Pregnancy & Lactation
The safety of Diclofenac eye drops in pregnancy & lactation has not been established and its use therefore is not recommended unless the potential benefit to the mother outweighs the possible risk to the child.
Drug Interaction
No drug interaction is reported. There should be at least 5 minutes interval when another ophthalmic solution (e.g., steroid) is given.
Storage
Close the bottle immediately after use. Do not use for more than four weeks after opening. Store at room temperature.
Commercial Packaging
Intafenac 0.1% eye drops: Dropper bottle of 5 ml.
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