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Marlox Plus (Magaldrate & Simethicone)
Therapeutic Group: Gastro Intestinal Disorders » Antiulcerant » Antacid
Presentation

Marlox Plus Tablet: Each tablet contains Magaldrate BP 480 mg and Simethicone USP 20 mg.

Marlox Plus Suspension: Each 5ml contains Magaldrate BP 480 mg and Simethicone USP 20 mg.

Descriptions
Marlox Plus is a combination of magaldrate and simethicone. Magaldrate (magnesium aluminium compound i.e. Hydroxymagnesium Aluminate), which neutralizes gastric acid extraordinarily quickly without raising the pH above 5-6. It also decreases the activity of pepsin in gastric secretion. Besides this, simethicone, the another component of Marlox Plus, enables the gas buble to coalesce and give relief from flatulence.
Indications
Marlox Plus is indicated to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux and hiatal hernia. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis and esophagitis. Magaldrate may be given to children if necessary. Also indicated for the relief of flatulence, abdominal distension and windy colic.
Dosage & Administration
Tablet: 1-3 Marlox Plus tablet, after meals and at bed time or as directed by the physician.
Suspension: 2-4 teaspoonfuls after 20-60 minutes of meal and before sleep or on the basis of physician’s prescription.
Side Effects
GI side-effects are uncommon. Occasionally, if excessive amount is consumed, diarrhea, constipation or regurgitation may occur.
Precautions
Care should be taken in decreased kidney function, hypophosphataemia and weak people.
Contraindications
Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.
Use in Pregnancy & Lactation
Pregnant women: Magaldrate may be used in pregnancy if indicated. However one should avoid excessive dosage.
Lactating mother: Magaldrate may pass into breast milk but has not been reported to cause problem in nursing babies.
Drug Interaction
It should not be used in patients taking any form of Tetracycline. The drug may cause reduced bio-availability or slower absorption of a number of drugs including propranolol, isoniazid, prednisolone and naproxen.
Overdose
Over dosage with this formulation is a rare case.
Commercial Packaging
Marlox Plus Tablet: Each box contains 10 blister strips of 10 tablets.
Marlox Plus Suspension: Bottle containing 200ml of syrup.
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