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Simplovir Cream (Aciclovir)
Therapeutic Group: Anti Viral » Herpes Simplex & Varicella Zoster Medication
Simplovir Cream

Simplovir cream: Each gram cream contains Aciclovir BP 50 mg.

Aciclovir is a synthetic purine derivative. It exerts its antiviral effect on Herpes simplex viruses (HSV) and Varicella zoster (VZV) virus by interfering with DNA synthesis and inhibiting viral replication. In cells infected with virus, the antiviral activity of Aciclovir appears to depend principally on the intracellular conversion of the drug to Aciclovir triphosphate which is the pharmacologically active form of the drug.
Aciclovir cream is indicated for the treatment of initial and recurrent labial and genital Herpes simplex infections.
Dosage & Administration
Aciclovir should be applied to lesions every 4 hours for 5 days. If, after 5 days, healing is not complete then treatment may be continued for a further 5 days. The affected area should be kept clean and dry. In case of genital Herpes simplex infection patients should be wear loose-fitting cloths to avoid irritation to the lesions or as directed by the physician.
Side Effects
Edema, pain, pruritus, rash may occur
Aciclovir cream is not recommended for application to buccal or vaginal mucous membrane. Care should be taken to avoid accidental introduction into the eye.
The drug is contraindicated in those patients with a history of hypersensitivity to Aciclovir or any of the components of the preparation.
Use in Pregnancy & Lactation
Pregnancy: Pregnancy category B.
Lactation: It is not known whether this drug is excreted in human milk.
Commercial Packaging
Simplovir Cream: Each tube contains 5 gm cream.
Products from the same therapeutic group
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Entecavir 0.5 & 1 mg Tablet
Adefovir Dipivoxil 10 mg Tablet
Lamivudine 100 mg Tablet
Tenofovir Disoproxil Fumarate 300 mg Tablet
Hepatitis C Medication
Ribavirin 200 mg capsule
Sofosbuvir tablet
Sofosbuvir INN and Velpatasvir INN Tablet
Ledipasvir 90 mg and Sofosbuvir 400 mg tablet
Daclatasvir tablet
Herpes Simplex & Varicella Zoster Medication
Aciclovir Tablet & IV Infusion
Simplovir Cream
Aciclovir BP 5%
Valacyclovir Hydrochloride Tablet
Influenza Medication
Oseltamivir capsule

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