Home > Products > Pyrazone
Share Print This Page

Pyrazone (Sulphinpyrazone)
Therapeutic Group: Anti Gout » Uricosuric Agent

Pyrazone : Each tablet contains Sulfinpyrazone BP 200 mg.

Pyrazone helps to remove excess uric acid from the body. Too much uric acid can cause gout or gouty arthritis. Certain illness or medications can increase uric acid level. It can help to reduce the risk of complications (such as kidney stones) that can occur if uric acid levels in the blood are too high (hyperuricemia).It completely inhibits the reabsorption of uric acid at the proximal convoluted tubule, thereby facilitating urinary excretion of uric acid and decreasing plasma urate concentrations.
Pyrazone is indicated for the treatment of:

Chronic gouty arthritis

Intermittent gouty arthritis

Dosage & Administration
200-400 mg daily in two divided doses, with meals or milk, gradually increasing when necessary to full maintenance dosage in one week.
Side Effects
The symptoms are upset stomach, vomiting, loss of appetite and joint pain. If you experience any of the following symptoms like difficulty in breathing, tightness in the chest, skin rash, unusual bleeding, fever, sore throat and mouth sores, call your doctor immediately.
Patients receiving Pyrazone should be kept under close medical supervision and periodic blood counts are recommended. It may be administered with care to patients with a history of healed peptic ulcer. It is suggested that Pyrazone should be used with caution in conjunction with sulfa drugs, the sulfonylurea hypoglycemic agents and insulin. Because Pyrazone is a potent uricosuric agent, it may precipitate urolithiasis and renal colic, especially in the initial stages of therapy. For this reason, an adequate fluid intake and alkalinization of the urine are recommended. Salicylates antagonize the uricosuric action of Pyrazone and for this reason, their concomitant uses are contraindicated in gouty arthritis.
Patients with an active peptic or symptoms of gastro-intestinal inflammation or ulceration should not receive the drug. The drug is contraindicated in patients with a history or the presence of hypersensitivity to phenylbutazone or other pyrazoles.
Use in Pregnancy & Lactation
Pyrazone is in the FDA pregnancy category C. This means that it is not known whether Pyrazone will harm an unborn baby. Don't take Pyrazone without first talking to your doctor if you are pregnant.
It is also not known whether Pyrazone passess into breast milk. Do not take it without first talking to your doctor if you are breast-feeding a baby.
Nausea, vomiting, diarrhea, epigastric pain, laboured respiration, convulsions and coma. Treatment:
No specific antidote. Induce emesis, gastric lavage, supportive treatment (intravenous glucose infusions).
Commercial Packaging
Pyrazone : Each box contains 2 strips of 10 Tablets.
400 mg daily, given in two divided doses, as above. This dosage may be increased to 800 mg daily, if necessary and may sometimes be reduced to as low as 200 mg daily after the blood urate level has been controlled.
Products from the same therapeutic group
Anti Gout
Colchicine USP 0.5 mg and 0.6 mg tablet
Uricosuric Agent
Xanthine Oxidase Inhibitor
Allopurinol tablet
Febuxostat 40 and 80 mg tablet

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin sneakers shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest christian louboutin model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first louboutin schuhe. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like louboutin. Sometimes, you will find louboutin damen schuhe online. But they are high quality louboutin schuhe deutschland. Best louboutin schuhe outlet for girls. The 1:1 christian louboutin are also perfect. Luxury louboutin schoenen for sale online.