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Travast (Travoprost)
Therapeutic Group: Ophthalmic » Anti Glaucoma Preparations
Presentation
Travast

Travast sterile eye drops: Each ml contains 40 microgram of Travoprost USP.

Descriptions
Travoprost is a clear, colorless to slightly yellow oil. Travast ophthalmic solution is supplied as sterile, buffered aqueous solution of travoprost.
Indications
Decrease of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Dosage & Administration
Use in adults
One drop in the affected eye once-daily in the evening. The dosage of Travast should not exceed once daily since it has been shown that more frequent administration may decrease the normal intraocular pressure.

Paediatric patients
The efficacy and safety of travoprost eye drops in patients below the age of 18 years have not been established.
Side Effects
The most common ocular adverse effect is ocular hyperemia. Ocular adverse events reported at an incidence of 5-10% included decreased visual acuity, eye discomfort, foreign body sensation, pain, and pruritus. Ocular adverse events reported at an incidence of 1-4% included, abnormal vision, blepharitis, blurred vision, cataract, conjunctivitis, dry eye, flare, iris discoloration, keratitis, lid margin crusting, photophobia, subconjunctival hemorrhage, and tearing.
Precautions
Travast eye drops should be used with caution in patients with active intraocular inflammation & macular edema. In case of patients with mild to severe hepatic impairment and renal impairment (creatinine clearance as low as 14 ml/min) no dosage adjustment is necessary. Travast should not be administered while wearing contact lenses. Lenses may be reinserted 15 minutes following administration of Travast eye drop.
Contraindications
Hypersensitivity to travoprost or to any of the excipients.
Use in Pregnancy & Lactation
Pregnancy category C. It is unknown whether travoprost from eye drops is excreted in human breast milk. Animal studies have shown excretion of travoprost and metabolites in breast milk. The use of Travast by breast-feeding mothers is not recommended.
Drug Interaction
No specific interaction was observed with Travast eye drops.
Overdose
No cases of overdose have been reported.
Storage
Store in a cool, dry place and protected from light.
Keep out of reach of children.
Discard the container 4 weeks after opening.
Commercial Packaging
Travast sterile eye drops: Plastic dropper bottle contains 3 ml of sterile eye drops.
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