Home > Products > Edeloss
Share Print This Page

Edeloss (Frusemide & Spironolactone)
Therapeutic Group: Cardiovascular » Anti Hypertensive » Diuretic
Presentation

Edeloss: Each film coated tablet contains Frusemide BP 20 mg & Spironolactone BP 50 mg.

Edeloss Plus: Each film coated tablet contains Frusemide BP 40 mg & Spironolactone BP 50 mg.

Descriptions
Edeloss is a combination drug, containing a short-acting loop-diuretic, Frusemide and a long-acting aldosterone antagonist, potassium-sparing Spironolactone. Preparation of these two, shows complementary mechanism of action to result in a powerful diuretic effect. Frusemide inhibits Na+/K+/2Cl- co-transport at loop of Henle and there occurs inhibition of electrolyte and water reabsorption and Spironolactone acts on collecting tubule to block the aldosterone receptors competitively thus inhibiting sodium retention and potassium secretion. As a result sodium excretion is largely enhanced & loss of potassium is suppressed thus a total positive effect on diuresis is achieved.
Indications
• Essential hypertension

• Chronic congestive heart failure

• Hepatic cirrhosis, with collection of fluid in the abdominal cavity (ascites)

• Swelling due to excess fluid retention (edema)

• Hyperaldosteronism

• Resistant edema associated with secondary hyperaldosteronism
Dosage & Administration
Edeloss: 1 to 4 tablets daily, orally, according to the patient\'s response.
Edeloss Plus: For previously stabilized patients 1 to 2 tablets daily, orally.
Side Effects
Generally, this combination preparation is well tolerated. However, a few side effects like nausea, malaise or gastric upset, headache, hypotension, skin rash may be seen which disappears after withdrawal of the drug.
Precautions
Caution should be taken in patients liable to electrolyte deficiency. This preparation should also be used with caution in diabetes, enlarged prostate, hypotension and in hypovolemia.
Contraindications
The combination of Frusemide and Spironolactone is contraindicated in patients with acute renal failure, renal insufficiency (creatinine clearance: <30ml/min), anuric states, hyperkalemia, hyponatremia, addison\'s disease or in patients with hypersensitivity to Frusemide, Spironolactone or Sulphonamide. It is also contraindicated for children.
Use in Pregnancy & Lactation
Pregnancy: There is clinical evidence of safety of Frusemide in pregnancy but Spironolactone may cross the placental barrier. So it should be used in pregnancy only if strictly indicated & for short-term treatment and if expected benefits to the mother is greater than the possible risk to the fetus.
Lactation: It is contraindicated in lactating mother.
Drug Interaction
Precautions should be taken while co-administration with the following drugs: ACE inhibitors, nephrotoxic & ototoxic antibiotics, corticosteroids, NSAIDs, carbenoxolone and sucralfate.
Overdose
Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. due to excessive diuresis. Treatment should be aimed at the replacement of fluid and correction of any electrolyte imbalance.
Commercial Packaging
Edeloss: Each box contains 5 blister strips of 10 tablets.
Edeloss Plus: Each box contains 5 blister strips of 10 tablets.
Products from the same therapeutic group
Cardiovascular
Anti Anginal
Angifix
Isosorbide-5-Mononitrate
Feelnor
Trimetazidine Dihydrochloride tablet
Ivaprex
Ivabradine Hydrochloride
Ralozine
Ranolazine 500 mg
Trocer
Nitroglycerin 2.6 mg Capsule & Tablet
Trocer Spray
Nitroglycerin 0.4 mg Spray
Anti Coagulant
Parinox
Enoxaparin Sodium BP
Roxarel
Rivaroxaban 10 & 15 mg Tablet
Warin
Warfarin tablet
Anti Fibrinolytic
Intrax
Tranexamic acid BP
Anti Hypertensive
ARB Plain
Osartil
Losartan Potassium Tablet
Valsartil
Valsartan tablet
Xyotil
Olmesartan Medoxomil 20 & 40 mg Tablet
ACE Inhibitor Plain
Ramoril
Ramipril tablet
ACE Inhibitor Combination
Benadip
Benazepril plus Amlodipine
Indapril
Indapamide and Perindopril Erbumine
Ramoril Plus
Ramipril & Hydrochlorothiazide Tablet
β-Blocker
Carvista
Carvedilol 6.25, 12.5 & 25 mg tablet
Presonil
Metoprolol tartrate
Bisopro
Bisoprolol Fumarate 2.5 & 5 mg Tablet
Calcium Channel Blocker
Larcadip
Lercanidipine Hydrochloride film-coated tablet
Veracal
Verapamil hydrochloride
Amlotab
Amlodipine tablet
Lacidip
Lacidipine 2 mg & 4 mg Tablet
Centrally Acting Antihypertensive
Sardopa
Methyldopa
Combined Antihypertensive Preparations
Fixocard
Amlodipine plus Atenolol tablet
Osartil Plus
Losartan Potassium & Hydrochlorothiazide Tablet
Amlosartan
Amlodipine & Valsartan tablet
Valsartil Plus
Valsartan & Hydrochlorothiazide tablet
Xyotil Plus
Olmesartan Medoxomil plus Hydrochlorothiazide
Bisopro Plus
Bisoprolol fumarate and Hydrochlorothiazide tablet
Diuretic
Acuren
Hydrochlorothiazide tablet
Edeloss
Frusemide & Spironolactone Tablet
Idatix
Indapamide 1.5 mg Tablet
Epleron
Eplerenone 25 mg Tablet
Inospiron
Spironolactone 25 mg Tablet
Bumecard
Bumetanide 1 mg, 5 mg Tablet and 2 mg/4 ml IV/IM Injection
Anti Platelet
Integril
Eptifibatide INN
Lopirel
Clopidogrel tablet
Lopirel Plus
Clopidogrel & Aspirin Tablet
Prasurel
Prasugrel Hydrochloride INN tablet
Ticarel
Ticagrelor 90 mg Tablet
Lipid Lowering
Ezetim
Ezetimibe Tablet
Nicosit
Inositol nicotinate tablets
Nofiate
Fenofibrate Capsule
Ridel  ER
Niacin USP 500 mg Extended Release tablet
Rocovas
Rosuvastatin 5 & 10 mg Tablet
Syncard
Atorvastatin 10 mg and Amlodipine 5 mg
Tiginor
Atorvastatin 10, 20 & 40 mg tablet
Sympathomimetics / Inotropes
Adrinor
Adrenaline 1 mg/ml IV, IM, SC injection
Dobutin
Dobutamine Hydrochloride USP
Myomine
Dopamine Hydrochloride BP Injection
 
 

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin sneakers shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest christian louboutin model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first louboutin schuhe. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like louboutin. Sometimes, you will find louboutin damen schuhe online. But they are high quality louboutin schuhe deutschland. Best louboutin schuhe outlet for girls. The 1:1 christian louboutin are also perfect. Luxury louboutin schoenen for sale online.