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Idatix (Indapamide)
Therapeutic Group: Cardiovascular » Anti Hypertensive » Diuretic
Presentation
Idatix

Idatix 1.5 SR: Each sustained release coated tablet contains Indapamide BP 1.5 mg.

Descriptions
Indapamide, a thiazide type diuretic, has an anti-hypertensive action causing a drop in systolic, diastolic and mean blood pressure. Indapamide is also used to help reduce extra salt and water from the body. Idatix is first of all a new formulation, which maintains plasma levels at optimal values, 24 hours a day, and which eliminates excessive plasma peaks.

The certainty of perfect, 24-hour antihypertensive efficacy, in all hypertensive patients controlled by Idatix.

The certainty of an antihypertensive efficacy maintained in the long-term and due to the reduction of the dose strength with this new form, the certainty of an even better acceptability and safety of use.
Indications
Idatix (Indapamide) is indicated in the management of mild to moderate hypertension.
Dosage & Administration
One tablet daily, preferably in the morning.
Side Effects
Side-effects include dizziness, headache, anorexia, gastric irritation, nausea, vomiting, constipation and diarrhoea.Indapamide produces minimal diuresis. However, hyperuricaemia and hypokalaemia may occur and potassium supplementation may be required. Serum potassium should be monitored in patients prone or sensitive to hypokalaemia (such as patients treated concomitantly with steroids, digitalis or laxative drugs). Uric acid should be monitored, particularly in patients with a history of gout, who should continue to receive the appropriate treatment.
Indapamide (one tablet) daily can be administered to hypertensive patients with impaired renal function, and to those undergoing chronic haemodialysis, as there is no evidence of drug accumulation. However, the treatment should be discontinued if increasing azotemia or oliguria occur.
Precautions
Monitoring of potassium and uric acid serum levels is recommended, especially in subjects with a predisposition or sensitivity to hypokalaemia and in patients with gout.
Although no allergic manifestations have been reported during clinical trials, patients with a history of allergy to sulfonamide derivatives should be closely monitored.
Contraindications
• Hypersensitivity to sulfonamides
• Severe renal failure
• Hepatic encephalopathy or severe hepatic failure
• Hypokalaemia
Use in Pregnancy & Lactation
There are no adequate and well-controlled studies in pregnant women and so Indapamide is not recommended. Mothers taking Indapamide should not breast feed.
Overdose
Symptoms: These could include: allergies, skin rashes, epigastric pain, nausea, photosensitivity, dizziness, weakness and paraesthesia.

Treatment: Treatment is supportive and symptomatic, directed at correcting the electrolyte abnormalities.
Commercial Packaging
Idatix 1.5 SR: Each box contains 5 blister strips of 10 tablets.
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