Active ingredient: Enoxaparin Sodium BP.
Solvent: Water for injections BP.
Each ml of the solution contains: 10000 anti-Xa IU equivalent to 100 mg Enoxaparin Sodium.
Parinox 40: Each pre-filled syringe (0.4ml) contains 4000 anti-Xa IU is equivalent to 40 mg Enoxaparin Sodium BP.
Parinox 60: Each pre-filled syringe (0.6ml) contains 6000 anti-Xa IU is equivalent to 60 mg Enoxaparin Sodium BP.
Parinox 80: Each pre-filled syringe (0.8ml) contains 8000 anti-Xa IU is equivalent to 80 mg Enoxaparin Sodium BP.
Treatment of deep vein thrombosis, with or without pulmonary embolism.
Treatment of unstable angina and non-Q-wave myocardial infarction, administered concurrently with
Prevention of thrombus formation in the extra-corporal circulation during haemodialysis.
Prophylaxis of venous thromboembolic disease (prevention of blood clot formation in the veins), in
particular those which may be associated with orthopedic or general surgery.
Prophylaxis of venous thromboembolic disease in medical patients bedridden due to acute illness,
including cardiac insufficiency, respiratory failure, severe infections, rheumatic diseases.
No dosage adjustment is required in patients with moderate (creatinine clearance 30-50 ml/min) and mild (creatinine clearance 50-80 ml/min) renal impairment. But, all such patients should be observed carefully for signs and symptoms of bleeding.
For patients with severe (creatinine clearance <30 ml/min) renal impairment the dosage adjustment for Prophylactic dose is: 2000 IU once daily and Therapeutic dose is: 100 IU/kg once daily.
Elderly: No dosage adjustment is necessary, unless kidney function is impaired.
Children: Safety and effectiveness of Enoxaparin in pediatric patients have not been established.
Pregnancy category B. In humans, there is no evidence that Enoxaparin crosses the placental barrier Enoxaparin should be used during pregnancy only if the physician has established a clear need. Enoxaparin is not recommended for use in pregnant women with prosthetic heart valves.
It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Enoxaparin injection is administered to nursing women.
Enoxaparin Sodium BP (0.4 ml) in a blister pack.
Parinox 60: Each box contains 1 pre-filled syringe containing 6000 anti-Xa IU is equivalent to 60 mg
Enoxaparin Sodium BP (0.6 ml) in a blister pack.
Parinox 80: Each box contains 1 pre-filled syringe containing 8000 anti-Xa IU is equivalent to 80 mg
Enoxaparin Sodium BP (0.8 ml) in a blister pack.