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Cavic C Plus (Vitamin C, Vitamin D & Calcium)
Therapeutic Group: Vitamins and Minerals
Presentation
Cavic C  Plus

Cavic-C Plus effervescent tablet: Each tablet contains Calcium Lactate Gluconate USP 1000 mg, Calcium Carbonate BP 327 mg, Ascorbic acid (Vitamin-C) BP 500 mg and Vitamin-D3 4 mg (eq. to Colecalciferol BP 400 IU).

Indications
•As an adjunct to specific therapy for osteoporosis

•Increased demand for Calcium, Vitamin-C and Vitamin-D such as pregnancy, lactation, period of rapid growing (in childhood, addoloscence) and in old age

•In osteomalacia

•The prevention and treatment of Calcium deficiency/Vitamin-D deficiency especially in the housebound and hospitalized elderly subjects

•As adjuvant in cold and influenza

•Postmenopausal syndromes

•Premenstrual symptoms

•In high body temperatures

•As alkalizing agent in conditions with systemic acidosis.
Dosage & Administration
Dosage of Cavic-C Plus should be individualized based on the demands in age, sex and various physiological (pregnancy & lactation) & disease conditions. In general the dosage is-
Adults and children above 7 years: 1 Cavic-C Plus effervescent tablet daily
Children 3-7 years: Half Cavic-C Plus effervescent tablet daily
Side Effects
The use of Calcium supplements has rarely given rise to mild gastrointestinal disturbances, such as constipation, flatulence, nausea, gastric pain and diarrhoea. Following administration of Vitamin-D supplements occasional skin rash has been reported. Hypercalciuria, and in rare cases hypercalcaemia have been seen in long-term treatment with Vitamin-D at high doses.
Precautions
Patients with mild to moderate renal failure or mild hypercalciuria should be supervised carefully. Periodic checks of plasma Calcium levels and urinary Calcium excretion should be made in patients with mild to moderate renal failure or mild hypercalciuria. In patients with a history of renal stones urinary Calcium excretion should be measured to exclude hypercalciuria. With long-term treatment it is advisable to monitor serum and urinary Calcium levels and kidney function, and reduce or stop treatment temporarily if urinary Calcium exceeds 7.5 mmol/24 hours. Allowances should be made for Calcium and Vitamin-D supplements from other sources.
Contraindications
Absolute contraindications are hypercalcaemia resulting from myeloma, bone metastases or other malignant bone disease, sarcoidosis; primary hyperparathyroidism and Vitamin-D overdosage. It is also contraindicated in severe renal failure and hypersensitivity to any of the tablet ingredients.
Use in Pregnancy & Lactation
During pregnancy and lactation treatment with Cavic-C Plus should always be under the direction of a physician. During pregnancy and lactation, requirements for Calcium and Vitamin-D are increased but in deciding on the required supplementation allowances should be made for availability of these agents from other sources. Overdoses of Vitamin-D have shown teratogenic effects in pregnant animals. Vitamin-D and its metabolites pass into the breast milk.
Overdose
The most serious consequence of acute or chronic overdose is hypercalcaemia due to Vitamin-D toxicity. Symptoms include nausea, vomiting, polyuria, and constipation. Chronic overdoses can lead to vascular and organ calcification as a result of hypercalcaemia. Treatment should consist of stopping all intakes of calcium and Vitamin-D and rehydration.
Commercial Packaging
Cavic-C Plus effervescent tablet: Each tube contains 10 effervescent tablets.
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