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Intaflam (Ibuprofen)
Therapeutic Group: Analgesic, Anti Inflammatory » Steroid
Presentation
Intaflam

Each film coated Intaflam 400 tablet contains Ibuprofen BP 400 mg

Descriptions
Ibuprofen is the first of the propionic acid derivatives. It is a non-steroidal anti-inflammatory drug which has both analgesic and antipyretic effect.
Indications
Intaflam 400 is indicated for the treatment of

* Sign and symptoms of rheumatoid arthritis, ankylosing spondylitis, osteoarthritis

and other non-rheumatoid arthropathies

* Non-articular rheumatic condition, such as frozen shoulder, bursitis, tendinitis,

tenosynovitis and low back pain

* Soft tissue injuries such as sprain,strain and post-operative pain

* Dysmenorrhea

* Dental pain
Dosage & Administration
Adult : For arthritic pain; the dosage range is from 0.9 gm to 2.4 gm per day. The usual dose is 400 mg, 3 - 4 times per day, preferably after food. The dose may be raised to a maximum of 2.4 g daily depending on the severity of symptoms at the time of initiating drug therapy or as patients fail to respond. After a satisfactory response has been achieved, the dose should be reviewed and adjusted as required and tapered gradually.
For mild to moderate pain : 400 mg 6 hourly or as demanded by the condition. Dysmenorrhea : 400 mg every 4 hours or as demanded by the condition.
Children : 20 mg per kg body weight daily in divided doses. In children weighing less than 30 kg, the total dosage should not exceed 500 mg. If gastrointestinal disturbances occur, Intaflam 400 should be given with food or milk
Side Effects
Usually Ibuprofen has a low incidence of side effects. The most frequent side effect being gastrointestinal disturbance. Peptic ulceration and gastrointestinal bleeding have been reported. Other side effects include headache, dizziness, nervousness, skin rash, pruritus, drowsiness, insomnia, blurred vision and other ocular reactions, hypersensitivity reaction, abnormal liver function tests, impairment of renal function, agranulocytosis and thrombocytopenia.
Precautions
Ibuprofen should be given with caution to patiens with bleeding disorders, cardiovascular diseases, peptic ulceration or a history of such ulceration, in those receiving coumarin anticoagulants and in patients with renal or hepatic impairment
Contraindications
It should not be given to patients with hypersnesitivity to Ibuprofen and to individuals who show nasal polyps, angioedema, bronchospastic reactivity to aspirin or other non-steroidal anti-inflammatory drugs. Ibuprofen should not be used in peptic ulcer or bleeding ulcer
Use in Pregnancy & Lactation
Ibuprofen is not recommended during pregnancy or for use in nursing mothers
Overdose
In case of overdose gastric lavage, correction of blood electrolytes (if necessary) may be done. There is no specific antidote for Ibuprofen
Commercial Packaging
Intaflam 400: Box containing 10 blister strips of 10 tablets
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