Home > Products > Adiponil
Share Print This Page

Adiponil (Orlistat)
Therapeutic Group: Anti Obesity
Presentation
Adiponil

Adiponil Capsule: Each capsule contains Orlistat INN 120 mg

Descriptions
Adiponil is a potent, specific and reversible long acting inhibitor of gastrointestinal lipases for obesity management that acts by inhibiting the absorption of dietary fat. It exerts its therapeutic activity in the human stomach and small intestine by forming a covalent bond with the active serine residue of the active site of gastric and pancreatic lipases. The inactivated enzymes are thus unable to hydrolyze the dietary fat in the form of triglycerides, into absorbable free fatty acids and monoglycerides. As undigested triglycerides are not absorbed, the resulting calorie deficit has a positive effect on weight control. Systemic absorption of the drug is therefore not needed for activity. At the recommended therapeutic dose of 120 mg three times a day, Orlistat inhibits dietary fat absorption by approximately 30 %.
Indications
Adiponil is indicated for long term treatment of significantly obese patients, including patients with risk factors associated with obesity, in conjunction with a mildly hypocaloric diet. Adiponil is also indicated in long term weight control such as weight loss, weight maintenance and prevention of weight regain
Dosage & Administration
The recommended dose of Adiponil is one 120 mg capsule three times a day with each main meal (during or upto 1 hour after the meal).
Side Effects
Generally Adiponil is well tolerated. However few side effects including oily spotting, flattus with discharge, faecal urgeney, oily evaculation, increased defaecation may be seen after administration of orlistat
Precautions
Patients should be advised to adhere to dietary guidelines. gastrointestinal events may increase when orlistat is taken with a diet high in fat (>30% of calories from fat). The daily intake of fat should be distributed over three main meals. If a meal is missed, the dose of orlistat may be omitted.
Contraindications
Orlistat is contraindicated in patients with chronic malabsorption syndrome, cholestasis and in patients with known hypersensitivity to orlistat or to any components of this product.
Use in Pregnancy & Lactation
There are no adequate and well controlled studies of orlistat in pregnant women. Orlistat is not recommended for use during pregnancy.
It is not known if orlistat is secreted in human breast milk. Orlistat should not be taken by nursing women.
Overdose
Single doses of 800 mg and multiple doses of up to 400 mg three times a day for 15 days have been studied in normal weight and obese subjects without significant adverse findings. If a significant overdose of orlistat occur, it is recommended that the patient be observed for 24 hours. Based on human and animal studies, any systemic effects attributable to the lipase inhibiting properties of orlistat should be rapidly reversible
Commercial Packaging
Adiponil capsule: Each box contains 1 blister strip of 10 capsules
Products from the same therapeutic group
Anti Obesity
Adiponil
Orlistat INN 120 mg capsules
 
 

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin sneakers shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest christian louboutin model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first louboutin schuhe. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like louboutin. Sometimes, you will find louboutin damen schuhe online. But they are high quality louboutin schuhe deutschland. Best louboutin schuhe outlet for girls. The 1:1 christian louboutin are also perfect. Luxury louboutin schoenen for sale online.