Home > Products > Carvista
Share Print This Page

Carvista (Carvedilol)
Therapeutic Group: Cardiovascular » Anti Hypertensive » β-Blocker
Presentation

Carvista 6.25 : Each film coated tablet contains Carvedilol INN 6.25 mg.

Carvista 12.5 : Each film coated tablet contains Carvedilol INN 12.5 mg.

Carvista 25 : Each film coated tablet contains Carvedilol INN 25 mg.

Descriptions
Carvista (Carvedilol) is a cardiovascular drug whose main pharmacological action is non-selective antagonism of β-adrenergic receptors but which also possesses appreciable α-adrenergic antagonistic activity. It also has antiproliferative properties and is a scavenger of reactive free oxidant radicals. It is used in the treatment of hypertension, angina pectoris and congestive heart failure.
Indications
Carvista (Carvedilol) is indicated for the treatment of mild or moderate {NYHA (New York Heart Association) class II or III} heart failure of ischemic or cardiomyopathic origin, in conjunction with digitalis, diuretics and ACE inhibitor, to reduce the progression of disease as evidenced by cardiovascular death, cardiovascular hospitalization, or the need to adjust other heart failure medications. Carvista (Carvedilol) may be used in patients unable to tolerate an ACE inhibitor. Carvista (Carvedilol) may be used in patients who are not receiving digitalis, hydralazine or nitrate therapy.
Dosage & Administration
In heart failure, initially 3.125 mg twice daily (with food) may be given, dose may be increased at intervals of at least 2 weeks to 6.25 mg twice daily, then to 12.5 mg twice daily, then to 25 mg twice daily. The dose may be increased to highest dose tolerated, maximum 25 mg twice daily in patients less than 85 kg body-weight and 50 mg twice daily in patients over 85 kg.
In hypertension initially 12.5 mg once daily, increased after 2 days to usual dose of 25 mg once daily; if necessary the dose may be further increased at intervals of at least 2 weeks to maximum 50 mg daily in single or divided doses.In elderly patients the initial dose of 12.5 mg daily may provide satisfactory control.
In angina pectoris the recommended dose for initiation of therapy is 12.5 mg twice daily for the first 2 days. Thereafter, the recommended dosage is 25 mg twice daily. For elderly patients, the maximum daily dose is 50 mg daily in divided doses.
Side Effects
Postural hypotension, dizziness, headache, fatigue, gastro-intestinal disturbances, bradycardia; occasionally diminished peripheral circulation, peripheral oedema and painful extremities, dry mouth, dry eyes, eye irritation or disturbed vision, impotence, disturbances of micturition, influenza-like symptoms, rarely angina, AV block, exacerbation of intermittent claudication or Raynaud's phenomenon, allergic skin reactions, exacerbation of psoriasis, nasal stuffiness, wheezing, depressed mood, sleep disturbances, paresthesia, heart failure, changes in liver enzymes, thrombocytopenia, leukopenia are also reported.
Precautions
Take caution in hepatic impairment and in heart failure monitor clinical status for 2-3 hours after initiation and after increasing each dose. Before increasing dose ensure that the renal function and heart failure are not deteriorating.
Contraindications
Carvedilol is contraindicated in patients with NYHA class IV (New York Heart Association Class IV) decompensated cardiac failure requiring intravenous inotropic therapy, bronchial asthma or related bronchospastic conditions, second or third-degree AV block, sick sinus syndrome (unless a permanent pacemaker is in place), cardiogenic shock or severe bradycardia. Therapy is not to be initiated in severe heart failure.
Use in Pregnancy & Lactation
Carvedilol should not be used during breast-feeding, since no studies have been performed in lactating women and animal studies have shown that carvedilol is excreted in breast milk. Safety and efficacy in children have not been established with carvedilol. Carvedilol should not be used during pregnancy as no studies have been performed in this group. Animal studies have shown that carvedilol crosses the placental barrier. No information is available on safety and efficacy of Carvedilol use in neonates.
Drug Interaction
Digoxin : In normal healthy volunteers a single dose of carvedilol taken together with a single dose of digoxin resulted in significantly increased levels of digoxin 24 hour later. Patients with congestive heart failure stabilized on digoxin have been given carvedilol concomitantly without any adverse effects. Increased monitoring of digoxin is recommended when initiating, adjusting, or discontinuing the dose of carvedilol.
Rifampin : Pretreatment with rifampin resulted in a 60% decrease in Cmax and AUC.
Warfarin : Carvedilol did not alter the in vitro plasma protein binding of warfarin.
Clonidine : b-receptor antagonists potentiate the pressor reaction which may follow sudden withdrawal of treatment with clonidine although, in theory, the a-blocking action of carvedilol should modify the pressure rise.
Commercial Packaging
Carvista 6.25 : Box containing 10 blister strips of 10 tablets.
Carvista 12.5 : Box containing 5 blister strips of 10 tablets.
Carvista 25 : Box containing 3 blister strips of 10 tablets.
Products from the same therapeutic group
Cardiovascular
Anti Anginal
Angifix
Isosorbide-5-Mononitrate
Feelnor
Trimetazidine Dihydrochloride tablet
Ivaprex
Ivabradine Hydrochloride
Ralozine
Ranolazine 500 mg
Trocer
Nitroglycerin 2.6 mg Capsule & Tablet
Trocer Spray
Nitroglycerin 0.4 mg Spray
Anti Coagulant
Parinox
Enoxaparin Sodium BP
Roxarel
Rivaroxaban 10 & 15 mg Tablet
Warin
Warfarin tablet
Anti Fibrinolytic
Intrax
Tranexamic acid BP
Anti Hypertensive
ARB Plain
Osartil
Losartan Potassium Tablet
Valsartil
Valsartan tablet
Xyotil
Olmesartan Medoxomil 20 & 40 mg Tablet
ACE Inhibitor Plain
Ramoril
Ramipril tablet
ACE Inhibitor Combination
Benadip
Benazepril plus Amlodipine
Indapril
Indapamide and Perindopril Erbumine
Ramoril Plus
Ramipril & Hydrochlorothiazide Tablet
β-Blocker
Carvista
Carvedilol 6.25, 12.5 & 25 mg tablet
Presonil
Metoprolol tartrate
Bisopro
Bisoprolol Fumarate 2.5 & 5 mg Tablet
Calcium Channel Blocker
Larcadip
Lercanidipine Hydrochloride film-coated tablet
Veracal
Verapamil hydrochloride
Amlotab
Amlodipine tablet
Lacidip
Lacidipine 2 mg & 4 mg Tablet
Centrally Acting Antihypertensive
Sardopa
Methyldopa
Combined Antihypertensive Preparations
Fixocard
Amlodipine plus Atenolol tablet
Osartil Plus
Losartan Potassium & Hydrochlorothiazide Tablet
Amlosartan
Amlodipine & Valsartan tablet
Valsartil Plus
Valsartan & Hydrochlorothiazide tablet
Xyotil Plus
Olmesartan Medoxomil plus Hydrochlorothiazide
Bisopro Plus
Bisoprolol fumarate and Hydrochlorothiazide tablet
Diuretic
Acuren
Hydrochlorothiazide tablet
Edeloss
Frusemide & Spironolactone Tablet
Idatix
Indapamide 1.5 mg Tablet
Epleron
Eplerenone 25 mg Tablet
Inospiron
Spironolactone 25 mg Tablet
Bumecard
Bumetanide 1 mg, 5 mg Tablet and 2 mg/4 ml IV/IM Injection
Anti Platelet
Integril
Eptifibatide INN
Lopirel
Clopidogrel tablet
Lopirel Plus
Clopidogrel & Aspirin Tablet
Prasurel
Prasugrel Hydrochloride INN tablet
Ticarel
Ticagrelor 90 mg Tablet
Lipid Lowering
Ezetim
Ezetimibe Tablet
Nicosit
Inositol nicotinate tablets
Nofiate
Fenofibrate Capsule
Ridel  ER
Niacin USP 500 mg Extended Release tablet
Rocovas
Rosuvastatin 5 & 10 mg Tablet
Syncard
Atorvastatin 10 mg and Amlodipine 5 mg
Tiginor
Atorvastatin 10, 20 & 40 mg tablet
Sympathomimetics / Inotropes
Adrinor
Adrenaline 1 mg/ml IV, IM, SC injection
Dobutin
Dobutamine Hydrochloride USP
Myomine
Dopamine Hydrochloride BP Injection
 
 

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin schoenen shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest replica handbags model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first replica designer handbags. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like replica handbags uk. Sometimes, you will find cheap replica handbags online. But they are high quality replica handbags. Best replica handbags outlet for girls. The 1:1 replica bags are also perfect. Luxury designer replica handbags for sale online.