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Reset (Paracetamol)
Therapeutic Group: Analgesic, Anti Inflammatory » NSAIDs/Non Opiod Analgesic
Presentation

Reset Tablet: Each tablet contains Paracetamol BP 500 mg.

Reset Syrup: Each 5 ml syrup contains Paracetamol BP 120 mg.

Reset Paediatric Drops: Each ml paediatric drops contains Paracetamol BP 80 mg.

Descriptions
Reset (Paracetamol) is a fast acting and safe analgesic with marked antipyretic property. It is specially suitable for patients who, for any reason, can not tolerate aspirin or other analgesics.
Indications
All conditions requiring relief from pain and fever such as neuritis, neuralgia, headache, toothache, earache, body ache, myalgia, minor arthritis pain, pain due to rheumatic disorder, cold, influenza, dysmenorrhoea etc.
Dosage & Administration
Tablet
Adult: 1 - 2 tablets every 4 to 6 hours up to a maximum of 4 g (8 tablets) daily
Children (6 - 12 years) : 1/2 to 1 tablet 3 to 4 times daily
Syrup
Children: 2 months: 60 mg (1/2 measuring spoonful) for post immunization pyrexia;
Under 3 months (on doctor's advice only) : 10 mg/kg (5 mg/kg if jaundiced)
3 months - 1 year : 60 - 120 mg (1/2 - 1 measuring spoonful),
1 - 5 years : 1 - 2 measuring spoonful
6 - 12 years : 2 - 4 measuring spoonful
Paediatric Drops
2 months: 60 mg for post-immunization pyrexia; under 3 months (on doctors advice only), 10 mg/kg (5 mg/kg if jaundiced); 3 months- 1 year: 60-120 mg; 1 - 5 years: 120-250 mg.

Paediatric drops may be given to children and neonates according to following guideline:

AgeDose of Paediatric Drops
0-3 months0.5 ml (upto 4 times daily)
4-11 months1 ml (upto 4 times daily)
12-23 months1.5 ml (upto 4 times daily)
2-3 years2 ml (upto 4 times daily)
4-5 months3 ml (upto 4 times daily)

Side Effects
Side effects of paracetamol are usually mild, though haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.
Precautions
Paracetamol should be given with care to patients with impaired kidney or liver function. Paracetamol should be given with care to patients taking other drugs that affect the liver.
Contraindications
Paracetamol is contraindicated in patients with severe renal function impairment and hepatic disease (Viral Hepatitis). Known hypersensitivity to paracetamol.
Overdose
Symptoms of Paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 40 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur.
Commercial Packaging
Reset: Box containing 20 blister strips of 10 tablets.
Reset Syrup: Bottle containing 60 ml syrup.
Reset Paediatric Drops: Bottle containing 15 ml Paediatric Drops.
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