Home > Products > Piodar
Share Print This Page

Piodar (Pioglitazone)
Therapeutic Group: Anti Diabetic » Oral hypoglycaemic
Presentation

Piodar 15 : Each tablet contains Pioglitazone Hydrochloride INN equivalent to Pioglitazone 15 mg.

Piodar 30 : Each tabl`0et contains Pioglitazone Hydrochloride INN equivalent to Pioglitazone 30 mg.

Descriptions
Piodar is a member of the newest class of oral antidiabetic agents called thiazolidinediones which depend on the presence of insulin for its mechanism of action. Piodar decreases insulin resistance in the periphery and in the liver resulting in increased insulin-dependent glucose disposal and decreased hepatic glucose output. It also improves abnormality in lipid metabolism by activating PPAR-γ receptor.
Indications
Piodar is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type II diabetes (NIDDM). Piodar is indicated for monotherapy and also indicated for use in combination with a sulfonylurea, metformin or insulin when diet and exercise plus the single agent does not result in adequate glycemic control.
Dosage & Administration
Piodar can be taken once daily without regard to meals. The management of antidiabetic therapy should be individualized. Piodar monotherapy in patients not adequately controlled with diet and exercise may be initiated at 15 mg or 30 mg once daily. For patients who respond inadequately to the initial dose of Piodar, the dose can be increased up to 45 mg once daily. For patients not responding adequately to monotherapy, combination therapy should be considered.
Side Effects
The overall incidence and types of adverse events reported in placebo controlled clinical trials of pioglitazone monotherapy at doses of 7.5 mg, 15 mg, 30 mg or 45 mg once daily are shown below :-
Upper respiratory tract infections13.2%, headache 9.1%, sinusitis 6.3%,myalgia 5.4%, tooth disorder 5.3%, pharyngitis 5.1%.
Precautions
Pioglitazone exerts its hypoglycemic effect only in the presence of insulin. Therefore it should not be used in patients with type I diabetes or for the treatment of diabetic ketoacidosis. Pioglitazone should be used with caution in case of combination therapy, hepatic insufficiency and heart diseases.
Contraindications
Pioglitazone is contraindicated in patients with known hypersensitivity to this product or any of its components.
Use in Pregnancy & Lactation
Pregnancy: There are no adequate and well controlled studies in pregnant women. Pioglitazone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Nursing Mothers: It is not known whether pioglitazone is secreted in human milk. Because many drugs are excreted in human milk, it should not be administered to a breast feeding women.
Drug Interaction
Administration of another thiazolidinedione with an oral contraceptive containing ethinyl estradiol and norethindrone reduces the plasma concentrations of both hormones by approximately 30%, which could result in loss of contraception.
Overdose
In the event of overdosage, appropriate supportive treatment should be initiated according to patient\'s clinical signs and symptoms.
Commercial Packaging
Piodar 15 : Each box contains 3 blister strips of 10 tablets.
Piodar 30 : Each box contains 3 blister strips of 10 tablets.
Products from the same therapeutic group
Anti Diabetic
Insulin and Its Preparations
Maxsulin
Human Insulin (rDNA)
Vibrenta
Insulin Glargine (rDNA) Injection
Oral hypoglycaemic
Compimet
Pioglitazone Hydrochloride & Metformin Hydrochloride
Consucon
Gliclazide
Linatab
Linagliptin INN
Linatab M
Linagliptin + Metformin HCl Tablet
Losucon
Glimepiride Tablet
Nobesit
Metformin Hydrochloride
Nomopil
Repaglinide 0.5,1,2 mg Raditab
Piodar
Pioglitazone tablet
Sitagil
Sitagliptin Phosphate INN
Sitagil M ER
Sitagliptin Phosphate Monohydrate INN 64.25 mg eq. to Sitagliptin 50mg & Metformin HCl BP 500 mg
 
 

Other christian louboutin outlet collection comes in mermaid shoes cut. There are two samples of louboutin schoenen shown in the pictures. Both shoes are different indeed with stylish and creative details on certain areas such as skirt, waist and chest. To match the latest replica handbags model, these mermaid cut wedding shoes a la princess of fairytale apply sweetheart strapless neckline cut. Thick ruffle details are applied on the first replica designer handbags. The ruffle application is combined with pleated details on the louboutin shoes uk. Thus, in conclusion, the christian louboutin schuhe is extremely very marvelous for your modern fairytale bridal. Women always like replica handbags uk. Sometimes, you will find cheap replica handbags online. But they are high quality replica handbags. Best replica handbags outlet for girls. The 1:1 replica bags are also perfect. Luxury designer replica handbags for sale online.