Therapeutic Group: Anti Histamine


Ebaril 10 tablet: Each film-coated tablet contains Ebastine BP 10 mg.

Ebaril syrup: Each 5 ml syrup contains Ebastine BP 5 mg.


Ebaril is a preparation of Ebastine. Ebastine is a long-acting and selective H1-histamine receptor antagonist. After repeated administration, inhibition of peripheral receptors remains at a constant level. Ebastine is rapidly absorbed and undergoes extensive first-pass metabolism following oral administration. Ebastine is almost totally converted to the pharmacologically active acid metabolite, Carebastine.


Ebaril is indicated for the symptomatic treatment of:

• Seasonal and perennial allergic rhinitis

• Idiopathic chronic urticaria

Dosage & Administration

• Children between 2 and 5 years: 2.5 ml (half teaspoonful) once daily (up to 5 ml in severe cases such as perennial allergic rhinitis)
• Children between 6 and 11 years: 5 ml (one teaspoonful) / 5 mg (half tablet) once daily (up to 10 ml in severe cases such as perennial allergic rhinitis)
• Adults and older children more than 11 years: 10 mg (1 tablet) or 10 ml (two teaspoonfuls) once daily.

Ebastine may be taken with or without food.

Side Effects

The most common side-effects are headache, dry mouth and drowsiness. Other less commonly reported side-effects include pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea and insomnia.


Caution is advised when used in hepatic impairment, renal insufficiency, QTc interval prolongation.

Use in Pregnancy & Lactation

The safety of Ebastine during pregnancy and lactation has not been established.